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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
34.85
Human Site:
Y459
Identified Species:
54.76
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
Y459
E
V
V
I
M
R
D
Y
Q
H
F
N
V
V
E
Chimpanzee
Pan troglodytes
XP_510301
627
67581
C415
P
G
T
Q
A
P
A
C
P
Q
V
V
I
M
R
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
Y459
E
V
V
I
M
R
D
Y
Q
H
F
N
V
V
E
Dog
Lupus familis
XP_544614
968
105825
Y746
E
V
V
I
M
R
D
Y
Q
H
L
N
V
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
Y460
E
V
V
I
M
R
D
Y
Q
H
L
N
V
V
E
Rat
Rattus norvegicus
Q62829
544
60692
Y332
I
V
N
Y
L
D
S
Y
L
V
G
D
E
L
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
T427
Q
E
R
S
G
Q
W
T
G
G
A
W
V
G
V
Chicken
Gallus gallus
XP_426393
667
74767
Y445
E
V
V
I
M
R
D
Y
Q
H
V
N
V
V
E
Frog
Xenopus laevis
NP_001082100
650
73749
Y432
E
V
V
I
M
R
D
Y
Q
H
E
N
V
V
E
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
Y471
E
V
V
I
M
R
D
Y
Q
H
R
N
V
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
E427
Y
H
H
P
N
I
V
E
T
Y
S
S
F
L
V
Honey Bee
Apis mellifera
XP_001122147
624
70155
M412
H
H
P
N
I
V
E
M
Y
D
S
F
L
V
D
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
L360
V
N
Y
L
D
S
Y
L
V
C
D
E
L
W
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S672
E
I
L
V
M
K
G
S
K
H
P
N
I
V
N
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
S726
E
I
L
V
M
K
E
S
S
H
P
N
I
V
N
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
93.3
13.3
N.A.
6.6
93.3
93.3
93.3
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
13.3
100
93.3
N.A.
93.3
33.3
N.A.
20
93.3
93.3
93.3
N.A.
20
33.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
7
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
7
47
0
0
7
7
7
0
0
7
% D
% Glu:
60
7
0
0
0
0
14
7
0
0
7
7
7
0
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
14
7
7
0
0
% F
% Gly:
0
7
0
0
7
0
7
0
7
7
7
0
0
7
0
% G
% His:
7
14
7
0
0
0
0
0
0
60
0
0
0
0
0
% H
% Ile:
7
14
0
47
7
7
0
0
0
0
0
0
20
0
0
% I
% Lys:
0
0
0
0
0
14
0
0
7
0
0
0
0
0
0
% K
% Leu:
0
0
14
7
7
0
0
7
7
0
14
0
14
14
0
% L
% Met:
0
0
0
0
60
0
0
7
0
0
0
0
0
7
0
% M
% Asn:
0
7
7
7
7
0
0
0
0
0
0
60
0
0
14
% N
% Pro:
7
0
7
7
0
7
0
0
7
0
14
0
0
0
0
% P
% Gln:
7
0
0
7
0
7
0
0
47
7
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
47
0
0
0
0
7
0
0
0
7
% R
% Ser:
0
0
0
7
0
7
7
14
7
0
14
7
0
0
0
% S
% Thr:
0
0
7
0
0
0
0
7
7
0
0
0
0
0
0
% T
% Val:
7
54
47
14
0
7
7
0
7
7
14
7
54
67
20
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
7
0
7
7
% W
% Tyr:
7
0
7
7
0
0
7
54
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _